DMPU is a versatile aprotic polar solvent for N-alkylation of chiral primary amines, O-alkylation of aldoses and the synthesis of poly (arylene ethers). It is an effective alternative to carcinogenic HMPA, As a highly reactive nucleophile and a co-solvent for the base; high Z-selectivity in enolate formation; DMPU exhibits non-mutagenicity and safety.
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone
Synonyms:DMPU; N,N'-Dimethyl-N,N'-trimethyleneurea; N,N'-Dimethylpropyleneurea
Molecular Formula:C6H12N2O
Molecular Weight:128.17
CAS:7226-23-5
EINECS:230-625-6
Density:1.064
Melting point:-20 ºC
Boiling point: 246 ºC
Refractive index:1.4875-1.4895
Flash point:121 ºC
Water solubility:soluble
Purity:99%
DMPU is a versatile aprotic polar solvent for N-alkylation of chiral primary amines, O-alkylation of aldoses and the synthesis of poly (arylene ethers). It is an effective alternative to carcinogenic HMPA, As a highly reactive nucleophile and a co-solvent for the base; high Z-selectivity in enolate formation; DMPU exhibits non-mutagenicity and safety.